December 14, 2022longevity

The Science Behind NMN

Nicotinamide mononucleotide (NMN) is a naturally occurring molecule that has recently gained attention for its potential benefits in supporting healthy aging and preventing age-related diseases. NMN is a precursor to nicotinamide adenine dinucleotide (NAD+), a coenzyme that plays a crucial role in energy production, DNA repair, and other important biological processes.

As we age, our levels of NAD+ tend to decrease, leading to a decline in the function of various systems in the body. Supplementation with NMN has been shown to increase NAD+ levels, potentially reversing some of the negative effects of aging and improving overall health and well-being.

In this article, we will discuss the potential benefits of NMN supplementation, including its effects on energy metabolism, DNA repair, and brain function. We will also discuss the current state of research on NMN and provide references for further reading.

One of the most well-known benefits of NMN supplementation is its potential to support healthy energy metabolism. NAD+ plays a key role in the production of ATP, the main source of energy for cells in the body. As we age, our NAD+ levels tend to decline, leading to a decrease in ATP production and resulting in fatigue and reduced physical performance.

Supplementation with NMN has been shown to increase NAD+ levels, which can improve ATP production and reduce fatigue. In a study published in the journal Cell Metabolism, mice fed a diet supplemented with NMN had increased NAD+ levels and improved exercise performance compared to mice fed a control diet.

NMN supplementation may also have benefits for DNA repair. DNA damage is a natural part of aging, and it can lead to a variety of age-related diseases, including cancer. NAD+ plays a crucial role in DNA repair, and a decline in NAD+ levels has been linked to an increased risk of DNA damage and age-related diseases.

Supplementation with NMN has been shown to increase NAD+ levels, which can improve DNA repair and reduce the risk of DNA damage. In a study published in the journal Nature, mice fed a diet supplemented with NMN had increased NAD+ levels and improved DNA repair compared to mice fed a control diet.

Another potential benefit of NMN supplementation is its effect on brain function. NAD+ is involved in various brain processes, including the regulation of neurotransmitter release and the maintenance of neuronal structure. As we age, NAD+ levels tend to decline, leading to a decline in brain function.

Supplementation with NMN has been shown to increase NAD+ levels, which can improve brain function and reduce the risk of age-related cognitive decline. In a study published in the journal Nature Communications, mice fed a diet supplemented with NMN had increased NAD+ levels and improved cognitive function compared to mice fed a control diet.

Currently, the research on the benefits of NMN supplementation is still ongoing , however, the available evidence suggests that NMN may have promising benefits for supporting healthy aging and preventing age-related diseases.

If you are interested in learning more about the potential benefits of NMN supplementation, here are a few references for further reading:

    1. Imai, S. (2020). NAD+ metabolism, aging, and age-related diseases. Annual Review of Biochemistry, 89, 173-194.

    2. Yoshino, J., Imai, S. (2011). NAD+ biosynthesis, aging, and age-related metabolic diseases. Trends in Endocrinology and Metabolism, 22(9), 464-471.

    3. Nakahata Y., Kaluzova M., Grimaldi B., et al. (2008) The NAD+−dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control. Cell, 134(2):329–340.

       

Written by Kristina Meyers

Leave a comment

All comments are moderated before being published

LEGAL DISCLAIMER: These products are not intended to diagnose, treat, cure, or prevent any disease. IVITA products will not prevent intoxication. Do not drink and drive while using these products. Please drink responsibly and never excessively consume alcohol. Keep out of the reach of children. Use under medical supervision. Always consult your doctor before you or anyone else consumes any drug, supplement, or food. Notify your doctor immediately if vomiting, diarrhea, decreased urination, or other signs of dehydration continue beyond 24 hours. Consult a doctor before using IVITA if you have heart or kidney disease, or electrolyte / fluid restrictions. These products are not labeled for sale outside the U.S. or Mexico.

REFUND POLICY: Due to the complexities of the human anatomy and each person's unique genetic makeup, IVITA products may not work for everyone. Therefore, we offer every customer a full refund on their first order up to 1 unit of ACTIVE, DETOX and ICARIA within 30 days of purchase if they didn’t feel better after using our product. Please note: No claim is being made, but rather a warranty that you can get your money back if you don't feel at least 50% better after using our product at the suggested dosages and let us know by sending a message or sending an email to hello@lifeivita.com prior to the end of the 30 day refund window. Please inspect your order upon reception and contact us immediately if the item is defective, damaged or if you receive the wrong item, so that we can evaluate the issue and make it right. If you receive damaged product(s), send us a message or send an email to hello@lifeivita.com within 30 days. When buying a unit, only the price of the unit(s) will be refunded, no shipping or additional units will be refunded. Due to the consumable nature of IVITA products, and our desire to decrease risk of tampering for our customers, we do not accept product returns.